Orale! Guajillo Peppers (12 Ounce) Guajillo peppers are used in Mexican cooking to add flavor, mild heat and color to various dishes. They’re frequently used in pastes or rubs to flavor different types of meats, such as pork, chicken and beef. In addition to Mexican moles, Guajillo is often used for enchiladas, salsas, sauces, soups, stews and the meat sauce in tamales. Guajillo’s unique flavor allows for the creation of sweet sauces as well. Guajillo peppers pair very well with chocolate.